Faculty-Industry Partnerships

Scott Laster

 

Professor

Biological Sciences

919.515.7958

scott_laster@ncsu.edu


Partnership Opportunities

Pharmaceutical development

Natural product development and testing

Biomedical sciences

Expertise

Discovery of new anti-inflammatory pharmaceuticals, use of natural products to control inflammation, discovery of novel mechanisms to control inflammation

Relevant Research Projects

Tetra-O-methyl nordihydroguaiaretic acid (Terameprocol) inhibits the NF-kB-dependent transcription of TNF-a and MCP-1/CCL2 genes by preventing RelA from binding its cognate sites on DNA. J. Inflamm., 2010.

Inhibition of H1N1 influenza A virus growth and induction of inflammatory mediators by
the isoquinoline alkaloid berberine and extracts of goldenseal (Hydrastis canadensis). Int. Immunopharmacol, 2011.

Ethanolic Echinacea purpurea extracts contain a mixture of cytokine-suppressive and cytokine-inducing compounds, including some that originate from endophytic bacteria. PLOS ONE, 2015.

Equipment/Facilities

1,200-square-foot lab equipped to study immunity and inflammation

Education

Ph.D., Biological Sciences, Florida State University, 1984

Selected Honors

Member, USDA animal health study section, 2011-2013

Member, Porcine Reproductive and Respiratory Syndrome Virus Regional Committee, USDA, 1999-2005

Associate editor, Journal of Immunology, 2001-2004. Various other editorial/review positions

Leader, NCSU Graduate Concentration in Immunology